Chev Chelios (Jason Statham), a hit man wanting to go straight, lets his latest target slip away, then he awakes the next morning to a phone call that informs him he has been poisoned and has only an hour to live unless he keeps adrenaline coursing through his body while he searches for an antidote.Crank is a 2006 American black comedy action film written and directed by Mark Neveldine and Brian Taylor and starring Jason Statham, Amy Smart and Jose Pablo Cantillo. The plot centers on a British hitman in Los Angeles named Chev Chelios who is poisoned and must keep his adrenaline flowing constantly in order to keep himself alive. He does so by various methods including taking drugs and getting into fights, while he tries to track down the man who poisoned him. The title of the film comes from the slang word for methamphetamine.

The film was followed by a sequel, titled Crank: High Voltage, in 2009.